Nano-TiCl4.SiO2: a versatile and efficient catalyst for synthesis of dihydropyrimidones via Biginelli condensation
Nano-TiCl4.SiO2 has been found to be an extremely efficient catalyst for the preparation of 3,4-dihydropyrimidinones/thiones via three-component reactions of an aldehyde, β-ketoester or β-diketone and urea or thiourea under mild conditions. Nano-TiCl4.SiO2 as a solid Lewis acid has been synthesized by reaction of nano-SiO2 and TiCl4. The structural characterization of this acid has been studied by FT-IR (ATR), XRD, SEM and TEM. This process was simple and environmentally benign with high to excellent yields. Furthermore, the catalyst could be recovered conveniently and reused for at least three times.
Saved in:
| Main Authors: | , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
The South African Chemical Institute
2014
|
| Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502014000100004 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|