Halogenated oxindole and indoles from the South African marine ascidian Distaplia skoogi
The known 3,6-dibromoindole (1), 6-bromo-3-chloroindole (2) and 6-bromo-2-oxindole (3) were isolated from the marine ascidian (sea squirt) Distapia skoogi collected from Algoa Bay, South Africa. Standard spectroscopic techniques were used to elucidate the structures of 1-3. All three compounds were found to be moderately cytotoxic to metastatic MDA-MB-231 breast cancer cells.
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Main Authors: | , , , , , |
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Format: | Digital revista |
Language: | English |
Published: |
The South African Chemical Institute
2013
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Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502013000100015 |
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