Microwave irradiation versus conventional heating in the synthesis of N-methyl-2-pyrrolidone catalyzed by highly active copper powder
A convenient one-pot synthesis of N-methyl-2-pyrrolidone is achieved either by conventional heating or microwave irradiation. The intermediate N-methyl-4-hydroxybutyramide formed from the exothermic reaction of 7-butyrolactone with aqueous methylamine undergoes an intramolecular condensation reaction catalyzed by highly active copper powder to form the pyrrolidone in good yield.
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| Main Authors: | , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
The South African Chemical Institute
2011
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| Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502011000100041 |
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