Ph3P catalyzed synthesis of alkyl 2-(4-oxopyridin-1(4H)-yl)acrylates by nucleophilic addition to alkyl propiolates
4-Hydroxypyridine undergoes a smooth reaction with alkyl propiolates in the presence of triphenylphosphine to produce α and β-substituted alkyl acrylate products. When the reaction was performed with 4-hydroxyquinoline only α-substituted alkyl acrylates were obtained.
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
The South African Chemical Institute
2010
|
| Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502010000100037 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
