Ph3P catalyzed synthesis of alkyl 2-(4-oxopyridin-1(4H)-yl)acrylates by nucleophilic addition to alkyl propiolates
4-Hydroxypyridine undergoes a smooth reaction with alkyl propiolates in the presence of triphenylphosphine to produce α and β-substituted alkyl acrylate products. When the reaction was performed with 4-hydroxyquinoline only α-substituted alkyl acrylates were obtained.
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Main Authors: | , , , |
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Format: | Digital revista |
Language: | English |
Published: |
The South African Chemical Institute
2010
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Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0379-43502010000100037 |
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