CHILD syndrome: successful treatment of skin lesions with topical lovastatin and cholesterol lotion

Abstract: CHILD syndrome (Congenital Hemidysplasia, Ichthyosiform erythroderma, Limb Defects) is a rare X-linked dominant disease. The authors report a 2-month-old patient presenting with typical features of CHILD syndrome that was treated with a topical solution containing cholesterol and lovastatin, with complete clearance of her CHILD nevus. The changes in skin lipid metabolism that explain the CHILD ichthyosiform nevus and their correction through topical application of cholesterol and lovastatin are discussed.

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Bibliographic Details
Main Authors: Sandoval,Karina Romero, Machado,Maria Cecília Rivitti, Oliveira,Zilda Najjar Prado de, Nico,Marcello Menta Simonsen
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2019
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962019000300341
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