Thalidomide in plasma cell balanitis refractory to conventional topical treatment

Abstract: Zoon's plasma cell balanitis is a chronic genital inflammatory dermatosis that affects uncircumcised men, especially the elderly. It's characterized by painless erythematous plaques of orange hue, located on the glans penis and foreskin. Circumcision is the most effective treatment; however, it can be hard for patients to accept. As an alternative, topical calcineurin inhibitors are used, with good response. This article reports the case of a 32-year-old patient, HIV carrier, diagnosed with Zoon's plasma cell balanitis. Treatment with topical tacrolimus was administered, without improvement. A 6-week course of thalidomide resulted in complete remission of the lesions, without recurrence after eight months of follow-up.

Saved in:
Bibliographic Details
Main Authors: Serrão,Lucas Mariano, Sarmenghi,Karina Demoner de Abreu, Pinto,Barbara Christina Bonino Pereira, Miranda,Paulo Bittencourt de
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962018000600881
Tags: Add Tag
No Tags, Be the first to tag this record!