New drugs, new challenges for dermatologists: mucocutaneous ulcers secondary to everolimus

Abstract Everolimus, a mammalian target of rapamycin inhibitor, is an emerging drug, which is being increasingly applied in oncology and solid organ transplantation. Oral ulcers are a frequent side effect associated with this immunosupressor. We report the case of a renal transplant recipient who developed disfiguring oral and perianal ulcers secondary to everolimus's toxicity. This is probably the first report of perianal involvement. Dermatologists need to be aware of the potential mucocutaneous adverse effects related to these new drugs that are becoming evermore common in our clinical practice.

Saved in:
Bibliographic Details
Main Authors: Pasin,Victor Pavan, Pereira,Amanda Regio, Carvalho,Kalline Andrade de, Paiva,João Marcos Góes de, Enokihara,Milvia Maria Simões e Silva, Porro,Adriana Maria
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Dermatologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0365-05962015000700165
Tags: Add Tag
No Tags, Be the first to tag this record!