Convalescent plasma or hyperimmune immunoglobulin for people with COVID19
Convalescent plasma is being considered as a potential therapy for COVID-19. We highlight and contextualise the findings of a recent Cochrane rapid review that evaluated the effectiveness and safety of convalescent plasma or hyperimmune immunoglobulin transfusion in the treatment of people with COVID-19. The review found low-certainty evidence of the therapeutic effectiveness and safety of convalescent plasma. As the novel coronavirus continues to spread in South Africa (SA), convalescent plasma may offer a therapeutic ray of hope for mitigating the morbidity and mortality burdens of the disease. Further investigation of the clinical benefits of the therapy in well-designed studies is needed to provide more evidence that will guide COVID-19 treatment decision-making in the SA context.
| Main Authors: | , , , , |
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| Format: | Digital revista |
| Language: | English |
| Published: |
South African Medical Association
2020
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| Online Access: | http://www.scielo.org.za/scielo.php?script=sci_arttext&pid=S0256-95742020000800026 |
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