Behavior of adipokines after a year follow-up in the Obesity Outpatient Clinic for Children and Adolescents

Objective: demonstrate adipokines progression, along 12 months, in obese children and adolescents who attend the Obesity Outpatient Clinic for Children and Adolescents of the HCPA. Methods: children and adolescents in medical treatment for obesity were followed for 12 months, assessing anthropometry, blood pressure, waist circumference, lipid profile, fasting blood sugar and insulin, inter leukine- 6, tumor necrosis factor alpha, and adiponectin in two points in time: at inclusion and after 12 months follow-up in the Obesity Outpatient Clinic for Children and Adolescents. Results: 27 children and adolescents were assessed with median age of 10.3 years. The mean BMI z-scores lowered during this period (p < 0.01), HDL-c increased in the period (p = 0.025). The medians of adipokines did not vary during the period: IL-6 (p = 0.470), TNF-&#945; (p = 0.753) and adiponectin (p = 0.943). There was no correlation of IL-6 and TNF-&#945; with central and global obesity along the 12-months follow-up. Adiponectin increased in 45% of the sample, the increase being more pronounced in females. Conclusion: children and adolescents in medical treatment for obesity, after one-year follow-up, did not improve their adiponectin profile.

Bibliographic Details

Main Authors:	Miraglia,Fernanda, Moraes Silveira,Carla Rosane de, Gomes Beghetto,Mariur, Oliveira,Fernanda dos Santos, Mello,Elza Daniel de
Format:	Digital revista
Language:	English
Published:	Grupo Arán 2015
Online Access:	http://scielo.isciii.es/scielo.php?script=sci_arttext&pid=S0212-16112015001000019
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