New papulovesicular rash in the course of COVID-19 signaling viral reactivation

SUMMARY Cutaneous manifestations are considered an infrequent presentation of coronavirus disease 2019 (COVID-19) and are mostly described in outpatient settings. Its onset during the course of the severe COVID-19 disease has been poorly described in severe cases. Studies focused on dermatological manifestations mostly described maculopapular or pernio-like lesions and less frequently vesicular or varicella-like eruption. We described the occurrence of a vesiculopapular eruption in three laboratory-confirmed COVID-19 patients associated with severe lung injury in whom the skin findings preceded viral reactivation and recrudescence of hypoxemia. The potential mechanisms for COVID-19-related cutaneous manifestations include immune hypersensitivity, cytokine-release syndrome, deposition of microthrombi, and vasculitis.

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Bibliographic Details
Main Authors: Rihl,Marcos Frata, Fendt,Lúcia Costa Cabral, Nedel,Wagner Luis
Format: Digital revista
Language:English
Published: Associação Médica Brasileira 2021
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0104-42302021000300182
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