Systemic coccidioidomycosis in a dog in Northeastern Brazil

ABSTRACT: We described a case of systemic infection by Coccidioides sp. in a dog. An adult, mixed breed, free-ranging male dog presented with clinical signs that included apathy, cachexia, anorexia, limited mobility with sternal recumbency, bilateral mucopurulent ocular discharge, dyspnoea, pulmonary crepitation, erosive and nodular lesions on the skin, and swelling and stiffness of the left tibiotarsal joint. The dog was submitted to a postmortem examination. Grossly, there were multiple yellow to white nodules in various organs. Histologically, the lesions were characterized as pyogranulomatous inflammation associated with fungal spherules morphologically consistent with Coccidioides sp. The dog was concomitantly diagnosed with undifferentiated sarcoma affecting the skin, lymph nodes, liver, and testicles. The diagnosis of coccidioidomycosis was made based on the histologic changes associated with morphotintorial features and positive immunolabeling of organisms with anti-Coccidioides immunohistochemistry. This case demonstrated that Coccidioides sp. can infect dogs that inhabit urban centers in the semiarid region of Northeastern Brazil, likely due to exposure to dust from contaminated environments.

Bibliographic Details

Main Authors:	Alves,Rodrigo Cruz, Campos,Édipo Moreira, Silva,Raquel Annes Fagundes, Batista,Samara Tereza Morais, Carneiro,Rosileide dos Santos, Rissi,Daniel Ricardo, Galiza,Glauco José Nogueira de, Dantas,Antônio Flávio Medeiros
Format:	Digital revista
Language:	English
Published:	Universidade Federal de Santa Maria 2021
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782021001200553
Tags:	Add Tag No Tags, Be the first to tag this record!