New Allyldithiocarbimates: Synthesis, Structure and Antifungal Activity against Phakopsora pachyrhizi and Hemileia vastatrix

Twelve tetraphenylphosphonium allyldithiocarbimates were synthesized and fully characterized by high-resolution electrospray ionization mass spectrometry (HR-ESI-MS), infrared and nuclear magnetic resonance (NMR) spectroscopies. The spectroscopic data indicated that the allyldithiocarbimate anions present Z configuration, as confirmed by X-ray crystallography. These new compounds inhibited the germination of Phakopsora pachyrhizi and Hemileia vastatrix at very low doses, with IC50 (concentration to achieve 50% of inhibition of spore germination) values ranging from 0.028 to 0.166 mmol L-1, and IC90 (concentration to achieve 90% of inhibition of spore germination) values varying from 0.156 to 0.528 mmol L-1. Allyldithiocarbimate salts are lead compounds for the development of new antifungals for coffee leaf rust and Asian soybean rust, devastating plant diseases with limited control options.

Bibliographic Details

Main Authors:	Vidigal,Antonio E. C., Rubinger,Mayura M. M., Silva,Lucas F. da, Zambolim,Laércio, Pereira,Arthur B. D., Guilardi,Silvana, Souza,Rafael A. C., Ellena,Javier
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Química 2020
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532020000400703
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