New 1-hydroxy-1,1-bisphosphonates derived from 1H-pyrazolo[3,4-b]pyridine: synthesis and characterization
A number of 1H-pyrazolo[3,4-b]pyridine derivatives, starting from 2-chloro-3-formyl pyridine, was synthesized to obtain new 1-hydroxybisphosphonates, a class of compounds with potential biological interest. Spectroscopic data were used to characterize all compounds and to identify N-1 and N-2 regioisomers, and mono-and bisphosphonates derivatives. X-ray diffractometry studies of compound 7a confirmed the proposed structure.
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Main Authors: | , , , , , , |
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Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2013
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532013000800010 |
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