Microwave-assisted reaction of 2,3-dichloronaphthoquinone with aminopyridines

The synthesis of pyridylaminonaphthoquinones by microwave-assisted reaction of 2,3-dichloro-1,4-naphthoquinone with aminopyridines is described. The use of microwave irradiation diminished the reaction times and improved the yields substantially in all these reactions. The compounds were tested for their cytotoxic activities against MCF-7 breast cancer cell line.

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Bibliographic Details
Main Authors: Tapia,Ricardo A., Cantuarias,Lorena, Cuéllar,Mauricio, Villena,Joan
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2009
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532009000500027
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