Synthesis of novel PETT analogues: 3,4-dimethoxy phenyl ethyl 1,3,5-triazinyl thiourea derivatives and their antibacterial and anti-HIV studies

3,4-Dimethoxy phenyl ethyl-1,3,5-triazinyl thiourea derivatives (8a-o and 9a-o) were prepared by condensation of 2,4,6-trichloro-1,3,5-s-triazine (1) with 4-hydroxy coumarin (2), 3,4-dimethoxy phenyl ethyl thiourea (4) and various substituted phenyl urea/thiourea (6a-o/7a-o) and tested for their antibacterial and anti-HIV activities against different microorganisms. The structures of novel synthesized compounds have been established on the basis of ¹H NMR, IR and Elemental Analysis.

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Bibliographic Details
Main Authors: Patel,Rakesh B., Chikhalia,Kishor H., Pannecouque,Christophe, Clercq,Erik de
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2007
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532007000200011
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