Solid-phase synthesis of isoalloxazines using merrifield resin
The reaction of Merrifield resin bound diamino compounds with alloxan monohydrate gave 7-resin bound 10-substituted isoalloxazines that were characterized by solid phase fluorescence and IR spectroscopy. The resin was cleaved by 40% aqueous HF/DMF to give 7-carboxy-10-substituted isoalloxazines that were characterized by UV-vis., IR, ¹H NMR, fluorescence and elemental analysis.
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Main Authors: | , , |
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Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2006
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Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532006000200030 |
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