Synthesis and biological activity of three new 5a-hydroxy spirostanic brassinosteroid analogues

Three new spirostanic brassinosteroid analogues have been synthesized for the first time from diosgenin: (25R)-2alpha,3alpha-epoxy-5alpha-hydroxyspirostan-6-one (3), (25R)-2beta,3alpha,5alpha-trihydroxyspirostan-6-one (5) and (25R)-2beta-methoxy-3alpha,5alpha-dihydroxyspirostan-6-one (6). In the radish hypocotyl elongation and cotyledon expansion bioassay compound 3 showed plant growth promoting activity whereas 6 was shown to be phytotoxic.

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Bibliographic Details
Main Authors: Rodríguez,Caridad R., Villalobos,Yohan I., Becerra,Esther A., Manchado,Francisco C., Herrera,Deysma C., Zullo,Marco A. T.
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Química 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50532003000300022
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