The Preparation and Intramolecular Radical Cyclisation Reactions of Chiral Oxime Ethers
Chiral oxime ether 2 and Oxime ester 4 have been prepared by alkylation and esterification of the oxime 1. Racemic hydroxylamine 6 and chiral hydroxylamine 10 have been synthesised from N-hydroxysuccinimide and the corresponding alcohol in the presence of diethylazodicarboxylate, the two products were converted into the oxime ethers 7 and 11 respectively. The intramolecular radical cyclisation reactions of these oxime ethers and esters has been studied, successful reaction was observed to produce alkyl hydroxylamines 3, 8 and 12.
Saved in:
| Main Authors: | , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
1998
|
| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0103-50531998000400012 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|