Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs

PURPOSE: To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%. METHODS: Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels. RESULTS: The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033). CONCLUSION: The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.

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Main Authors: Martins,Apóstolo Ferreira, Borges,Naida Cristina, Coutinho,Priscila Vaz, Lemes,Aline Rodrigues, Silva,Ashbel Schneider da, Barbosa,Rayssa Kossa, Paulo,Neusa Margarida
Format: Digital revista
Language:English
Published: Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000675
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spelling oai:scielo:S0102-865020150010006752016-01-05Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigsMartins,Apóstolo FerreiraBorges,Naida CristinaCoutinho,Priscila VazLemes,Aline RodriguesSilva,Ashbel Schneider daBarbosa,Rayssa KossaPaulo,Neusa Margarida Chitosan Peritoneum Surgical Mesh Swine PURPOSE: To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%. METHODS: Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels. RESULTS: The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033). CONCLUSION: The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.info:eu-repo/semantics/openAccessSociedade Brasileira para o Desenvolvimento da Pesquisa em CirurgiaActa Cirúrgica Brasileira v.30 n.10 20152015-10-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000675en10.1590/S0102-865020150100000004
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country Brasil
countrycode BR
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databasecode rev-scielo-br
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region America del Sur
libraryname SciELO
language English
format Digital
author Martins,Apóstolo Ferreira
Borges,Naida Cristina
Coutinho,Priscila Vaz
Lemes,Aline Rodrigues
Silva,Ashbel Schneider da
Barbosa,Rayssa Kossa
Paulo,Neusa Margarida
spellingShingle Martins,Apóstolo Ferreira
Borges,Naida Cristina
Coutinho,Priscila Vaz
Lemes,Aline Rodrigues
Silva,Ashbel Schneider da
Barbosa,Rayssa Kossa
Paulo,Neusa Margarida
Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
author_facet Martins,Apóstolo Ferreira
Borges,Naida Cristina
Coutinho,Priscila Vaz
Lemes,Aline Rodrigues
Silva,Ashbel Schneider da
Barbosa,Rayssa Kossa
Paulo,Neusa Margarida
author_sort Martins,Apóstolo Ferreira
title Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
title_short Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
title_full Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
title_fullStr Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
title_full_unstemmed Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
title_sort acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs
description PURPOSE: To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%. METHODS: Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels. RESULTS: The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033). CONCLUSION: The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.
publisher Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia
publishDate 2015
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000675
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