Acute systemic response to intraperitoneal implantation of polypropylene mesh/chitosan-based film composite in pigs

PURPOSE: To assess the systemic response of pigs to the intraperitoneal implantation of polypropylene mesh associated with chitosan-based film with a degree of deacetylation of 95%. METHODS: Blood samples were collected 24 hours before, and two and seven days after surgery. Systemic reactions were evaluated based on white blood cell count, C-reactive protein, and total serum protein, albumin and globulin levels. RESULTS: The systemic response was proportional to the composite response induced by polypropylene mesh, and the tissue inflammatory response was higher in the PP group (p=0.0033). CONCLUSION: The polypropylene mesh/chitosan-based film composite did not elicit a systemic response in pigs.

Bibliographic Details

Main Authors:	Martins,Apóstolo Ferreira, Borges,Naida Cristina, Coutinho,Priscila Vaz, Lemes,Aline Rodrigues, Silva,Ashbel Schneider da, Barbosa,Rayssa Kossa, Paulo,Neusa Margarida
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2015
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015001000675
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