Hemodynamic, ventilatory and gasometric evaluation of an experimental bronchopleural fistula

PURPOSE:To investigate the hemodynamic and ventilatory changes associated with the creation of an experimental bronchopleural fistula (BPF) treated by mechanical ventilation and thoracic drainage with or without a water seal.METHODS :Six large white pigs weighing 25 kg each which, after general anesthesia, underwent endotracheal intubation (6mm), and mechanically ventilation. Through a left thoracotomy, a resection of the lingula was performed in order to create a BPF with an output exceeding 50% of the inspired volume. The chest cavity was closed and drained into the water sealed system for initial observation of the high output BPF.RESULTS:Significant reduction in BPF output and PaCO2 was related after insertion of a water-sealed thoracic drain, p< 0.05.CONCLUSION: Insertion of a water-sealed thoracic drain resulted in reduction in bronchopleural fistula output and better CO2 clearance without any drop in cardiac output or significant changes in mean arterial pressure.

Bibliographic Details

Main Authors:	Oliveira,Douglas Guimaraes de, Toneloto,Maria Gabriela Cavicchia, Moreira,Marcos Mello, Bustorff-Silva,Joaquim Murray, Souza,Gabriel Franco de, Martins,Luiz Claudio, Kosour,Carolina, Dragosavac,Desanka, Falcão,Antonio Luis Eiras
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira para o Desenvolvimento da Pesquisa em Cirurgia 2015
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-86502015000100001
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