GC-MS analysis and cardiovascular activity of the essential oil of Ocotea duckei

The essential oils obtained by steam distillation from the roots, stems, leaves and fruits of Ocotea duckei had their composition analyzed by GC-MS. The pharmacological activity of these oils was also evaluated showing significant cardiovascular effects. Forty-nine substances were identified, consisting of a complex mixture of monoterpenes (45%) and sesquiterpenes (55%). The fruits yielded (1.9%) more essential oil than the stems (1.0%), roots (0.8%) and leaves (0.7%). The main component in the oil of the leaves was trans-caryophyllene (60.54%), in the stem bark beta-eudesmol (27.51%) and in the fruits, dl-limonene (30.12%). The predominant essential oil component in the roots was elemol (24.31%). In non-anaesthetized normotensive rats, the essential oils from different parts of Ocotea duckei (leaves, fruits, stem and roots) induced significant (p < 0.05) hypotension followed by bradycardia.

Bibliographic Details

Main Authors:	Barbosa-Filho,José M., Cunha,Renildo M., Dias,Celidarque S., Athayde-Filho,Petrônio F., Silva,Marcelo S., da-Cunha,Emídio Vasconcelos L., Machado,Maria Iracema L., Craveiro,Afrânio A., Medeiros,Isac A.
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Farmacognosia 2008
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-695X2008000100009
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