First insights into the genetic diversity of Mycobacterium tuberculosis strains in Salvador, Bahia State, Brazil

This study constitutes a first attempt to describe the genetic population structure of Mycobacterium tuberculosis circulating in Salvador, Bahia State, Brazil. A total of 56 confirmed cases of pulmonary tuberculosis, identified between March and June 2008, were analyzed using restriction fragment length polymorphism (IS6110-RFLP). The study population was characterized by a predominance of males (71.43%) over 30 years of age (68.75%). Forty-one isolates were found to belong to a single pattern (73.2%), while 15 (26.7%) were found in group patterns, forming six clusters. The higher level of diversity observed is much more suggestive of endogenous reactivation than recent transmission.

Bibliographic Details

Main Authors:	Silva,Aída Cristina do Nascimento, Ferrazoli,Lucilaine, Simonsen,Vera, Reis,Joice Neves, Pereira,Susan Martins, Carmo,Theomira Mauadie de Azevedo, Mota,Eduardo Luiz Andrade, Reis,Mitermayer Galvão
Format:	Digital revista
Language:	English
Published:	Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz 2011
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2011000900019
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