Compliance with and response to hepatitis B vaccination in remaining quilombo communities in Central Brazil

Compliance with and responses to the hepatitis B vaccine were evaluated in remaining quilombo communities in Central Brazil. A total of 708 individuals who were susceptible to hepatitis B virus infection were invited to participate in the hepatitis B vaccination program in eight communities. Although 567 (80%) individuals received the first dose, only 198 (28%) complied with the full vaccination scheme. Of 148 subjects who agreed to be tested for anti-HBs, 123 (83.1%; 95%CI: 75.9-88.6) responded to the vaccine. A geometric mean titer of 512mIU/mL (95%CI: 342.5-765.3) was found. Male sex and older age were independently associated with non-response. Additional health education programs and alternative hepatitis B vaccine schedules are needed to improve the vaccination coverage in these communities in Central Brazil.

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Bibliographic Details
Main Authors: Motta-Castro,Ana Rita C., Gomes,Selma A., Yoshida,Clara F. T., Miguel,Juliana C., Teles,Sheila A., Martins,Regina M. B.
Format: Digital revista
Language:English
Published: Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz 2009
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2009000400004
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