The Acre Project: the epidemiology of malaria and arthropod-borne virus infections in a rural Amazonian population

The authors describe the baseline malaria prevalence and arbovirus seroprevalence among 467 subjects in an ongoing cohort study in rural Amazonia. Most subjects (72.2%) reported one or more previous episodes of malaria, and 15.6% had been hospitalized for malaria, but only 3.6% of individuals five years or older had malaria parasites detected by microscopy (10 with Plasmodium vivax and 4 with P. falciparum). Antibodies to Alphavirus, Orthobunyavirus, and/or Flavivirus were detected by hemagglutination inhibition (HI) in 42.6% of subjects aged five years or older, with a higher seropositivity rate among males (49.2%) than females (36.2%). Since 98.9% of subjects had been immunized for yellow fever, the presence of cross-reactive antibodies to dengue and other Flaviviruses cannot be ruled out, but at least 12 subjects (3.3%) with IgM antibodies to dengue virus detected by ELISA had a putative recent exposure to this virus.

Bibliographic Details

Main Authors:	Silva-Nunes,Mônica da, Malafronte,Rosely dos Santos, Luz,Bruna de Almeida, Souza,Estéfano Alves de, Martins,Lívia Carício, Rodrigues,Sueli Guerreiro, Chiang,Jannifer Oliveira, Vasconcelos,Pedro Fernando da Costa, Muniz,Pascoal Torres, Ferreira,Marcelo Urbano
Format:	Digital revista
Language:	English
Published:	Escola Nacional de Saúde Pública Sergio Arouca, Fundação Oswaldo Cruz 2006
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-311X2006000600021
Tags:	Add Tag No Tags, Be the first to tag this record!