Multicentric lymphoma with metastasis in the central nervous system in a dog

Multicentric lymphoma was diagnosed in a two-year-old dog with respiratory distress, dysorexia, abdominal enlargement and generalized lymphadenopathy. Immunohistochemical examination showed T-cell origin with CD3+ e CD79- expression. After five weeks, progressive neurological deficits and neoplastic lymphocytes were identified in the cerebrospinal fluid. Histopathological examination showed neoplastic cell invasion in the spleen, lymph nodes, cerebrum and cerebellum.

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Bibliographic Details
Main Authors: Aptekmann,K.P., Okamoto,C.E., Campos,K.C.H., Takahira,R.K.
Format: Digital revista
Language:English
Published: Universidade Federal de Minas Gerais, Escola de Veterinária 2005
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352005000300005
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