Erythropoietin resistance in end-stage renal disease patient with gastric antral vascular ectasia

Abstract We observed a case of recombinant human erythropoietin resistance caused by Gastric Antral Vascular Ectasia in a 40-year-old female with ESRD on hemodialysis. Some associated factors such as autoimmune disease, hemolysis, heart and liver disease were discarded on physical examination and complementary tests. The diagnosis is based on the clinical history and endoscopic appearance of watermelon stomach. The histologic findings are fibromuscular proliferation and capillary ectasia with microvascular thrombosis of the lamina propria. However, these histologic findings are not necessary to confirm the diagnosis. Gastric Antral Vascular Ectasia is a serious condition and should be considered in ESRD patients on hemodialysis with anemia and resistance to recombinant human erythropoietin because GAVE is potentially curable with specific endoscopic treatment method or through surgical procedure.

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Bibliographic Details
Main Authors: Lee,Desiree Ji Re, Fragata,Juliana, Pestana,José Osmar Medina, Draibe,Sergio, Canziani,Maria Eugênia, Cendoroglo,Miguel, Góes Jr.,Miguel Ângelo de
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Nefrologia 2015
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-28002015000200271
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