Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial

Abstract We investigate the impact of yacon syrup consumption on glycemic, lipid and metabolic endotoxemia in healthy subjects. Thus, 32 healthy were randomized into two groups that consumed 40 g of yacon syrup/day (= 8.74 g FOS/day) or a placebo, for 2-weeks. Anthropometric assessments, gastrointestinal effects, glycemic and lipid profile, and LPS were performed at the beginning and at the end of the study. The results obtained shown that the 2-weeks consumption of yacon syrup does not promote serum LPS alteration in healthy volunteers. Moreover, the glycemic and lipid profile were also similar between the groups before and after the intervention. Yacon syrup did not affect blood lipid, glucose or metabolic endotoxemia. However, it is possible that positive effects of yacon syrup will turn evident only in a long-term intervention. Further studies are needed to assess the long-term effect of yacon syrup consumption, and its use in obese and diabetic individuals.

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Main Authors: DIONÍSIO,Ana Paula, SILVA,Maria de Fátima Gomes da, CARIOCA,Antônio Augusto Ferreira, ADRIANO,Lia Silveira, ABREU,Fernando Antônio Pinto de, WURLITZER,Nedio Jair, PINTO,Claudia de Oliveira, PONTES,Dorasilvia Ferreira
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Ciência e Tecnologia de Alimentos 2020
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000100194
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spelling oai:scielo:S0101-206120200001001942020-05-29Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trialDIONÍSIO,Ana PaulaSILVA,Maria de Fátima Gomes daCARIOCA,Antônio Augusto FerreiraADRIANO,Lia SilveiraABREU,Fernando Antônio Pinto deWURLITZER,Nedio JairPINTO,Claudia de OliveiraPONTES,Dorasilvia Ferreira Smallanthus sonchifolius fructooligosaccharides prebiotics lipopolysaccharides Abstract We investigate the impact of yacon syrup consumption on glycemic, lipid and metabolic endotoxemia in healthy subjects. Thus, 32 healthy were randomized into two groups that consumed 40 g of yacon syrup/day (= 8.74 g FOS/day) or a placebo, for 2-weeks. Anthropometric assessments, gastrointestinal effects, glycemic and lipid profile, and LPS were performed at the beginning and at the end of the study. The results obtained shown that the 2-weeks consumption of yacon syrup does not promote serum LPS alteration in healthy volunteers. Moreover, the glycemic and lipid profile were also similar between the groups before and after the intervention. Yacon syrup did not affect blood lipid, glucose or metabolic endotoxemia. However, it is possible that positive effects of yacon syrup will turn evident only in a long-term intervention. Further studies are needed to assess the long-term effect of yacon syrup consumption, and its use in obese and diabetic individuals.info:eu-repo/semantics/openAccessSociedade Brasileira de Ciência e Tecnologia de AlimentosFood Science and Technology v.40 n.1 20202020-03-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000100194en10.1590/fst.38218
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language English
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author DIONÍSIO,Ana Paula
SILVA,Maria de Fátima Gomes da
CARIOCA,Antônio Augusto Ferreira
ADRIANO,Lia Silveira
ABREU,Fernando Antônio Pinto de
WURLITZER,Nedio Jair
PINTO,Claudia de Oliveira
PONTES,Dorasilvia Ferreira
spellingShingle DIONÍSIO,Ana Paula
SILVA,Maria de Fátima Gomes da
CARIOCA,Antônio Augusto Ferreira
ADRIANO,Lia Silveira
ABREU,Fernando Antônio Pinto de
WURLITZER,Nedio Jair
PINTO,Claudia de Oliveira
PONTES,Dorasilvia Ferreira
Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
author_facet DIONÍSIO,Ana Paula
SILVA,Maria de Fátima Gomes da
CARIOCA,Antônio Augusto Ferreira
ADRIANO,Lia Silveira
ABREU,Fernando Antônio Pinto de
WURLITZER,Nedio Jair
PINTO,Claudia de Oliveira
PONTES,Dorasilvia Ferreira
author_sort DIONÍSIO,Ana Paula
title Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
title_short Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
title_full Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
title_fullStr Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
title_full_unstemmed Effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
title_sort effect of yacon syrup on blood lipid, glucose and metabolic endotoxemia in healthy subjects: a randomized, double-blind, placebo-controlled pilot trial
description Abstract We investigate the impact of yacon syrup consumption on glycemic, lipid and metabolic endotoxemia in healthy subjects. Thus, 32 healthy were randomized into two groups that consumed 40 g of yacon syrup/day (= 8.74 g FOS/day) or a placebo, for 2-weeks. Anthropometric assessments, gastrointestinal effects, glycemic and lipid profile, and LPS were performed at the beginning and at the end of the study. The results obtained shown that the 2-weeks consumption of yacon syrup does not promote serum LPS alteration in healthy volunteers. Moreover, the glycemic and lipid profile were also similar between the groups before and after the intervention. Yacon syrup did not affect blood lipid, glucose or metabolic endotoxemia. However, it is possible that positive effects of yacon syrup will turn evident only in a long-term intervention. Further studies are needed to assess the long-term effect of yacon syrup consumption, and its use in obese and diabetic individuals.
publisher Sociedade Brasileira de Ciência e Tecnologia de Alimentos
publishDate 2020
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0101-20612020000100194
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