Autochthonous case of Canine Visceral Leishmaniasis in a non-endemic area in Minas Gerais, Brazil

ABSTRACT: Visceral Leishmaniasis by Leishmania infantum chagasi is an endemic zoonosis present in many areas of Brazil. This parasite needs reservoirs for maintenance of the infection and the presence of dogs in urban areas is a key factor for the spread of canine visceral leishmaniasis (CVL). The aim of this study was to report the first autochthonous case of CVL in the municipality of Iguatama, in west central region of Minas Gerais State. Dog infection by Leishmania infantum chagasi was confirmed in the municipality, previously considered as non-endemic area to CVL. The canine infection by Leishmania was confirmed by three immunological tests for antibodies: indirect immunofluorescence assay (IFA), rapid Dual Path Platform (DPP®) CVL immunochromatographic test, enzyme-linked immunosorbent assay (ELISA), and microscopic demonstration of Leishmania amastigotes in imprints of spleen and bone marrow stained by Giemsa. The species Leishmania infantum chagasi was confirmed by molecular diagnosis (PCR). Studies are being carried out, aiming to describe the importance and the prevalence of this disease in the region and factors associated with its transmission.

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Bibliographic Details
Main Authors: Faria,Mariana Teixeira de, Barbosa,Fernando S., Teixeira-Neto,Rafael G., Pinheiro,Guilherme R.G., Manhani,Marianna N., Marcelino,Andreza P., Barbosa,José Ronaldo, Fontes,Gilberto
Format: Digital revista
Language:English
Published: Colégio Brasileiro de Patologia Animal - CBPA 2017
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-736X2017001201505
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