Complete mole in a dichorionic twin pregnancy after intracytoplasmic sperm injection

A dichorionic twin pregnancy with complete hydatidiform mole and coexistent fetus is a rare and challenging situation, whose pathogenesis has not been yet fully understood. We present a case of a 39-year-old woman who underwent intracytoplasmic sperm injection with two embryos transfer. The 12-week gestation ultrasound examination revealed normal fetus and placenta with features of hydatidiform mole, leading to pregnancy termination. Autopsy and histological examinations diagnosed a complete mole coexisting with a normal fetus, and the genetic analysis showed a diploid fetus with biparental genome and molar tissue with paternal diploidy. This case highlighted that complete molar pregnancies may still occur even though pregnancy is achieved after intracytoplasmic sperm injection. A review of the literature was performed by collecting data from the few similar reported cases and by commenting on the pathogenesis of this rare condition.

Bibliographic Details

Main Authors:	Ferraz,Tiago José Santos de Matos, Bartosch,Carla Maria Magno, Ramalho,Carla Maria Almeida, Carvalho,Filipa Abreu Gomes de, Carvalho,Berta Cecília Campos Lima de, Brandão,Otília Gonçalves Bento Cavaleiro, Montenegro,Nuno Aires Mota Mendonça
Format:	Digital revista
Language:	English
Published:	Federação Brasileira das Sociedades de Ginecologia e Obstetrícia 2013
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-72032013000100008
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