A NOVEL POLYACRYLAMIDE-BASED HYDROGEL CROSSLINKED WITH CELLULOSE ACETATE AND PREPARED BY PRECIPITATION POLYMERIZATION

The synthesis of polyacrylamide-cellulose acetate hydrogels by precipitation polymerization in acetone solution is reported herein. These hydrogels exhibit smaller swelling ratios and larger compression moduli than homo polyacrylamide hydrogels. For cellulose acetate concentrations above 20 wt.%, hydrogels with N,N'-methylenebisacrylamide as a crosslinker exhibit swelling ratios and compression moduli similar to those of the hydrogels without the crosslinker. A possible explanation for this behavior is that cellulose acetate crosslinks polyacrylamide via free-radical reaction. The hydrogels obtained without the N,N'-methylenebisacrylamide crosslinker exhibit compression moduli up to 1.7 MPa, making them suitable for tissue engineering applications such as cartilage replacement.

Bibliographic Details

Main Authors:	Muñoz-García,Rubén O., Hernández,María E., Ortiz,Genaro G., Fernández,Víctor V. A., Arellano,Martín R., Sánchez-Díaz,Juan C.
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Química 2015
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422015000801031
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