Anxiolytic-like effects of erythrinian alkaloids from erythrina suberosa
Two alkaloids, erysodine (1) and erysothrine (2) were isolated from the flowers of a Pakistani medicinal plant, Erythrina suberosa. These compounds were investigated for anxiolytic properties, and the results showed significant effect, in an acute oral treatment with 1-2, which were suspended in saline (NaCl 0.9%) plus DMSO 1%, and evaluated in 122 Swiss male mice exposed to two tests of anxiety - the elevated plus-maze (EPM) and the light/dark transition model (LDTM).
Saved in:
Main Authors: | , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Sociedade Brasileira de Química
2011
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422011000500015 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|