Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae)
The effect of hydroalcoholic extracts (HE) obtained from leaves of Cissus sicyoides (CS) on glucose tolerance (GT) was investigated in rats treated with dexametasone (DEX). Our results showed that HE intensified the decreased GT promoted by (DEX). Additionally, the flavonoids kaempferol 3-O-rhamnoside and quercetin 3-O-rhamnoside, obtained from aerial parts of CS, were used to study the incorporation of glucose to glycogen in soleo muscle. The results showed that both flavonoids did not show effect on glycogen synthesis. Thus, our data, in contrast to popular believe, did not reveal antidiabetic activity to SC.
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Sociedade Brasileira de Química
2001
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oai:scielo:S0100-404220010006000142002-02-08Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae)Beltrame,Flávio LuísSartoretto,Juliano LuisBazotte,Roberto BarbosaCuman,Roberto NakamuraCortez,Diógenes Aparício GarciaFernandes,Luiz ClaudioTchaikovski,Osvaldo Cissus sicyoides Vitaceae antidiabetic potential flavonoids The effect of hydroalcoholic extracts (HE) obtained from leaves of Cissus sicyoides (CS) on glucose tolerance (GT) was investigated in rats treated with dexametasone (DEX). Our results showed that HE intensified the decreased GT promoted by (DEX). Additionally, the flavonoids kaempferol 3-O-rhamnoside and quercetin 3-O-rhamnoside, obtained from aerial parts of CS, were used to study the incorporation of glucose to glycogen in soleo muscle. The results showed that both flavonoids did not show effect on glycogen synthesis. Thus, our data, in contrast to popular believe, did not reveal antidiabetic activity to SC.info:eu-repo/semantics/openAccessSociedade Brasileira de QuímicaQuímica Nova v.24 n.6 20012001-12-01info:eu-repo/semantics/articletext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422001000600014pt10.1590/S0100-40422001000600014 |
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Beltrame,Flávio Luís Sartoretto,Juliano Luis Bazotte,Roberto Barbosa Cuman,Roberto Nakamura Cortez,Diógenes Aparício Garcia Fernandes,Luiz Claudio Tchaikovski,Osvaldo |
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Beltrame,Flávio Luís Sartoretto,Juliano Luis Bazotte,Roberto Barbosa Cuman,Roberto Nakamura Cortez,Diógenes Aparício Garcia Fernandes,Luiz Claudio Tchaikovski,Osvaldo Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae) |
| author_facet |
Beltrame,Flávio Luís Sartoretto,Juliano Luis Bazotte,Roberto Barbosa Cuman,Roberto Nakamura Cortez,Diógenes Aparício Garcia Fernandes,Luiz Claudio Tchaikovski,Osvaldo |
| author_sort |
Beltrame,Flávio Luís |
| title |
Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae) |
| title_short |
Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae) |
| title_full |
Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae) |
| title_fullStr |
Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae) |
| title_full_unstemmed |
Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae) |
| title_sort |
estudo fitoquímico e avaliação do potencial antidiabético do cissus sicyoides l. (vitaceae) |
| description |
The effect of hydroalcoholic extracts (HE) obtained from leaves of Cissus sicyoides (CS) on glucose tolerance (GT) was investigated in rats treated with dexametasone (DEX). Our results showed that HE intensified the decreased GT promoted by (DEX). Additionally, the flavonoids kaempferol 3-O-rhamnoside and quercetin 3-O-rhamnoside, obtained from aerial parts of CS, were used to study the incorporation of glucose to glycogen in soleo muscle. The results showed that both flavonoids did not show effect on glycogen synthesis. Thus, our data, in contrast to popular believe, did not reveal antidiabetic activity to SC. |
| publisher |
Sociedade Brasileira de Química |
| publishDate |
2001 |
| url |
http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422001000600014 |
| work_keys_str_mv |
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| _version_ |
1756387054748434432 |