Estudo fitoquímico e avaliação do potencial antidiabético do Cissus sicyoides L. (Vitaceae)

The effect of hydroalcoholic extracts (HE) obtained from leaves of Cissus sicyoides (CS) on glucose tolerance (GT) was investigated in rats treated with dexametasone (DEX). Our results showed that HE intensified the decreased GT promoted by (DEX). Additionally, the flavonoids kaempferol 3-O-rhamnoside and quercetin 3-O-rhamnoside, obtained from aerial parts of CS, were used to study the incorporation of glucose to glycogen in soleo muscle. The results showed that both flavonoids did not show effect on glycogen synthesis. Thus, our data, in contrast to popular believe, did not reveal antidiabetic activity to SC.

Saved in:
Bibliographic Details
Main Authors: Beltrame,Flávio Luís, Sartoretto,Juliano Luis, Bazotte,Roberto Barbosa, Cuman,Roberto Nakamura, Cortez,Diógenes Aparício Garcia, Fernandes,Luiz Claudio, Tchaikovski,Osvaldo
Format: Digital revista
Language:Portuguese
Published: Sociedade Brasileira de Química 2001
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40422001000600014
Tags: Add Tag
No Tags, Be the first to tag this record!