Spectrophotometric determination of cefaclor in pharmaceutical preparations
A simple spectrophotometric method is proposed for the determination of cefaclor. The method involves alkaline hydrolysis of the drug in ammonia buffer solution at pH 10 to yield diketopiperazine-2,5-dione derivative and subsequent measurement at 340 nm. Beer's law is obeyed in the concentration range 1.8 - 55 mg/mL. The proposed method was successfully applied to the determination of cefaclor in pharmaceutical formulations.
Saved in:
| Main Authors: | , , , |
|---|---|
| Format: | Digital revista |
| Language: | English |
| Published: |
Sociedade Brasileira de Química
1999
|
| Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0100-40421999000200011 |
| Tags: |
Add Tag
No Tags, Be the first to tag this record!
|