G26P[19] rotavirus A strain causing acute gastroenteritis in the American continent

In Brazil, the rotavirus A genotype G26 was first identified in suckling piglets, while the P[19] genotype has not been identified in any animal species so far. This report details the genetic characterisation of a G26P[19] RVA strain detected from an eight year-old child, vaccinated with Rotarix®, hospitalised with acute diarrhoeal disease in Rio de Janeiro in 2015. Most likely, the genome constellation (I5-R1-C1-M1-A8-N1-T1-E1-H1) observed in the G26P[19] Brazilian strain was a result of interspecies transmission events between humans and pigs. In addition, a rearrangement in the NSP5 gene was observed downstream of the 3’ non-coding region.

Bibliographic Details

Main Authors:	Gómez,Mariela M, Silva,Marcelle FM da, Volotão,Eduardo M, Fialho,Alexandre M, Mazzoco,Christian S, Rocha,Myrna S, Leite,José Paulo G
Format:	Digital revista
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 2018
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018001200401
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