Imported case of Dengue virus 3 genotype I in Rio de Janeiro state, Brazil

The dengue virus (DENV), of the genus Flavivirus (Flaviviridae), has four antigenically distinct serotypes, of which DENV-3 is classified into five genotypes. Here, we describe the detection of DENV-3 genotype I in sera of a Brazilian patient travelling from Singapore to Rio de Janeiro, Brazil, by using multiplex real-time RT-PCR, DNA sequencing of the whole envelope protein gene, and phylogenetic analysis. The virus shares ancestry with those identified in Bali, Indonesia, in 2015. It is possible that arboviruses such as Chikungunya ECSA genotype, DENV-4 genotype I, and Zika were introduced in Brazil from other continents during the multiple international events hosted by the country over the last four years, including World Youth Day, the Soccer World Cup, and the Summer Olympics.

Bibliographic Details

Main Authors:	Mendonça,Marcos César Lima de, Mares-Guia,Maria Angelica, Rodrigues,Cintia Damasceno dos Santos, Santos,Carolina Cardoso dos, Chalhoub,Flavia Lowen Levy, Araújo,Eliane Saraiva Machado, Chieppe,Alexandre Otávio, Nogueira,Rita Maria Ribeiro, Filippis,Ana Maria Bispo de
Format:	Digital revista
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 2018
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762018000800403
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