Oseltamivir-resistant influenza A(H1N1)pdm09 virus in southern Brazil
The neuraminidase (NA) genes of A(H1N1)pdm09 influenza virus isolates from 306 infected patients were analysed. The circulation of oseltamivir-resistant viruses in Brazil has not been reported previously. Clinical samples were collected in the state of Rio Grande do Sul (RS) from 2009-2011 and two NA inhibitor-resistant mutants were identified, one in 2009 (H275Y) and the other in 2011 (S247N). This study revealed a low prevalence of resistant viruses (0.8%) with no spread of the resistant mutants throughout RS.
Saved in:
Main Authors: | , , , , , , , , , |
---|---|
Format: | Digital revista |
Language: | English |
Published: |
Instituto Oswaldo Cruz, Ministério da Saúde
2013
|
Online Access: | http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000300392 |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|