Clonal multidrug-resistant Corynebacterium striatum within a nosocomial environment, Rio de Janeiro, Brazil

Corynebacterium striatum is a potentially pathogenic microorganism with the ability to produce outbreaks of nosocomial infections. Here, we document a nosocomial outbreak caused by multidrug-resistant (MDR) C. striatum in Rio de Janeiro, Brazil. C. striatum identification was confirmed by 16S rRNA and rpoB gene sequencing. Fifteen C. striatum strains were isolated from adults (half of whom were 50 years of age and older). C. striatum was mostly isolated in pure culture from tracheal aspirates of patients undergoing endotracheal intubation procedures. The analysis by pulsed-field gel electrophoresis (PFGE) indicated the presence of four PFGE profiles, including two related clones of MDR strains (PFGE I and II). The data demonstrated the predominance of PFGE type I, comprising 11 MDR isolates that were mostly isolated from intensive care units and surgical wards. A potential causal link between death and MDR C. striatum (PFGE types I and II) infection was observed in five cases.

Bibliographic Details

Main Authors:	Baio,Paulo Victor Pereira, Mota,Higor Franceschi, Freitas,Andréa D'avila, Gomes,Débora Leandro Rama, Ramos,Juliana Nunes, Sant'Anna,Lincoln Oliveira, Souza,Mônica Cristina, Camello,Thereza Cristina Ferreira, Hirata Junior,Raphael, Vieira,Verônica Viana, Mattos-Guaraldi,Ana Luíza
Format:	Digital revista
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 2013
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762013000100004
Tags:	Add Tag No Tags, Be the first to tag this record!