Cyclic 3'-5' guanosine monophosphate-dependent activity in Leishmania amazonensis

Although there are some data concerning the nitric oxide and the cyclic 3'-5'guanosine monophosphate (cGMP) signaling pathway in trypanosomatids, there is no report about the cGMP-dependent enzymatic activity identification. In this sense, a cGMP dependent activity was detected on soluble fraction from Leishmania amazonensis promastigotes with a high metacyclic level. This information is valuable in order to explore the metabolic pathway of G kinase protein in this parasite.

Saved in:
Bibliographic Details
Main Authors: Géigel,LF, Leon,LL
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2003
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000400012
Tags: Add Tag
No Tags, Be the first to tag this record!