A novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi

We report the molecular characterization of a novel reiterated family of transcribed oligo(A)-terminated, interspersed DNA elements in the genome of Trypanosoma cruzi. Steady-state level of transcripts of this sequence family appeared to be developmentally regulated, since only in the replicative forms the parasite showed expression of related sequences with a major band around 3 kb. The presence of frame shifts or premature stop codons predicts that transcripts are not translated. The sequence family also contains truncated forms of retrotransposons elements that may become potential hot spots for retroelement insertion. Sequences homologous to this family are interspersed at many chromosomes including the subtelomeric regions.

Bibliographic Details

Main Authors:	Verbisck,Newton Valério, Santos,Márcia Regina Machado dos, Engman,David M, Angel Chiurillo,Miguel, Ramirez,José Luis, Araya,Jorge Enrique, Mortara,Renato Arruda, Silveira,José Franco da
Format:	Digital revista
Language:	English
Published:	Instituto Oswaldo Cruz, Ministério da Saúde 2003
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762003000100016
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