Preliminary results on the effects of CD40/CD40L interactions and SAC-induction on IFN-gamma expression in human schistosomiasis

Preliminary results on the effects of CD40/CD40L interactions and SAC-induction on IFN-gamma expression in human schistosomiasis

In this communication the authors analyzed the pattern of expression of IFN-gamma as a surrogate type 1 response in different clinical forms of schistosomiasis in response to stimulation involving T-cell dependent and T-cell independent pathways, to investigate which pathways were functional in human schistosomiasis, and to further characterize the nature of Th1 response impairment in this parasitic disease.

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Bibliographic Details
Main Authors: Montenegro,Silvia ML, Abath,Frederico GC, Domingues,Ana LC, Melo,Wlademir, Morais,Clarice NL de, Coutinho,Eridan M, Mahanty,Siddhartha, Wynn,Thomas
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 2001
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02762001000900014
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