Induced tolerance to Schistosoma mansoni antigens modulates periovular granuloma

Immunological tolerance to Schistosoma mansoni antigens induced by oral exposure of neonatal and adult mice to adult worm, soluble egg and polysaccharide antigens conducted to modulated periovular granuloma of infected mice. However the tolerance do not interfere in the infection. The estimative population and subpopulation of lymphocytes in the spleen of tolerized (not infected) animals do not differ from normal animals but Lyt 2.2 reactive lymphocytes to Schistosoma antigens was demonstrated in the tolerized animals.

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Bibliographic Details
Main Authors: Sadigursky,Moysés, Falangola,Maria de Fátima, Santos,Rosella de Oliveira, Cardoso,Silvia Andrade, David,John
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1987
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761987000800050
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