Nasal secretions of Neisseria lactamica carriers have an inhibitory effect on Neisseria meningitidis attachment to human oroepithelial cells

Nasal secretions of volunteers colonized by N. lactamica impaired the attachment of N. lactamica and of meningococci of groups A and B to oroepithelial cells. Bacterial adherence was found to be mediated by nonpiliated adhesins with antigen(s) which probably are shared by the strains tested. Although a strong attachment-inhibiting activity arises in their nasal secretions, volunteers remained colonized by N. lactamica. This evidence suggest that the eradication of Neisseria carriage is a multifactorial event.

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Bibliographic Details
Main Authors: Andrade,João Ramos Costa, Marques,Margareth da Cunha, Santa Rosa,Milden Rodrigues de
Format: Digital revista
Language:English
Published: Instituto Oswaldo Cruz, Ministério da Saúde 1986
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0074-02761986000400013
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