Chemical constituents from the stem of Brosimum potabile (Moraceae)

Three coumarins, 5-methoxypsoralene, xanthyletin, and (-)-marmesin, have been isolated from the ethanolic extract of the stem of the Amazonian plant Brosimum potabile. The structures were determined on the basis of NMR analyses and by comparison with spectroscopic data in the literature. The analysis of the hexane fractions by GC-MS in EIMS mode suggested the presence of (1-methylpentyl)-benzene; α,α-dimethyl-4-(1-methylethyl)-benzenemethanol; 1-methyl-3,5-bis(1-methylethyl)-benzene; urs-12-ene; chola-5,22-dien-3β-ol; cholesta-4,6-dien-3β-ol; sitosteryl 9(Z)-octadecenoate; cholesta-5,22-dien-3β-ol; cholesta-4,6,22-trien-3-one; and cholesta-4,22-dien-3-one. NMR data of other hexane fractions indicated the presence of 3β-acetoxy-lup-12,20(29)-diene; 3β-acetoxy-olean-12-ene; 3β-acetoxy-urs-12-ene; and adian-5-ene. All these compounds are first described in B. potabile.

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Bibliographic Details
Main Authors: Abreu,Viviane Gomes da Costa, Silva,Marilda Conceição da, Magalhães,Rozângela Manfrini, Piló-Veloso,Dorila, Xavier,Izelene Felício da Silva, Oliveira,Patrícia Machado, Alcântra,Antônio Flávio de Carvalho
Format: Digital revista
Language:English
Published: Instituto Nacional de Pesquisas da Amazônia 2010
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0044-59672010000400011
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