Vancomycin-induced severe thrombocytopenia in a young infant

Vancomycin-induced severe thrombocytopenia in a young infant

Abstract Vancomycin is a first-line drug for treating methicillin-resistant Staphylococcus aureus. Thrombocytopenia is a rare adverse reaction to vancomycin treatment, and there are no reports of vancomycin-induced thrombocytopenia (VIT) in infants. We describe the case of a 3-month-old girl who was diagnosed with purulent meningitis. After 13 days of treatment with vancomycin, her platelet count reduced to 8 × 109/L. Vancomycin was discontinued, and intravenous methylprednisolone was administered. The platelet count returned to normal after 4 days. Patients, especially young children, receiving vancomycin for a long clinical course should undergo careful monitoring of laboratory indicators and blood tests.

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Main Authors: Chen,Quan-yao, Wan,Jun, Yang,Jian-hui, Lin,Min, Chen,Yao
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2018
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000600873
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spelling oai:scielo:S0037-868220180006008732018-11-28Vancomycin-induced severe thrombocytopenia in a young infantChen,Quan-yaoWan,JunYang,Jian-huiLin,MinChen,Yao Vancomycin Infants Thrombocytopenia Abstract Vancomycin is a first-line drug for treating methicillin-resistant Staphylococcus aureus. Thrombocytopenia is a rare adverse reaction to vancomycin treatment, and there are no reports of vancomycin-induced thrombocytopenia (VIT) in infants. We describe the case of a 3-month-old girl who was diagnosed with purulent meningitis. After 13 days of treatment with vancomycin, her platelet count reduced to 8 × 109/L. Vancomycin was discontinued, and intravenous methylprednisolone was administered. The platelet count returned to normal after 4 days. Patients, especially young children, receiving vancomycin for a long clinical course should undergo careful monitoring of laboratory indicators and blood tests.info:eu-repo/semantics/openAccessSociedade Brasileira de Medicina Tropical - SBMTRevista da Sociedade Brasileira de Medicina Tropical v.51 n.6 20182018-12-01info:eu-repo/semantics/reporttext/htmlhttp://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000600873en10.1590/0037-8682-0150-2018
institution SCIELO
collection OJS
country Brasil
countrycode BR
component Revista
access En linea
databasecode rev-scielo-br
tag revista
region America del Sur
libraryname SciELO
language English
format Digital
author Chen,Quan-yao
Wan,Jun
Yang,Jian-hui
Lin,Min
Chen,Yao
spellingShingle Chen,Quan-yao
Wan,Jun
Yang,Jian-hui
Lin,Min
Chen,Yao
Vancomycin-induced severe thrombocytopenia in a young infant
author_facet Chen,Quan-yao
Wan,Jun
Yang,Jian-hui
Lin,Min
Chen,Yao
author_sort Chen,Quan-yao
title Vancomycin-induced severe thrombocytopenia in a young infant
title_short Vancomycin-induced severe thrombocytopenia in a young infant
title_full Vancomycin-induced severe thrombocytopenia in a young infant
title_fullStr Vancomycin-induced severe thrombocytopenia in a young infant
title_full_unstemmed Vancomycin-induced severe thrombocytopenia in a young infant
title_sort vancomycin-induced severe thrombocytopenia in a young infant
description Abstract Vancomycin is a first-line drug for treating methicillin-resistant Staphylococcus aureus. Thrombocytopenia is a rare adverse reaction to vancomycin treatment, and there are no reports of vancomycin-induced thrombocytopenia (VIT) in infants. We describe the case of a 3-month-old girl who was diagnosed with purulent meningitis. After 13 days of treatment with vancomycin, her platelet count reduced to 8 × 109/L. Vancomycin was discontinued, and intravenous methylprednisolone was administered. The platelet count returned to normal after 4 days. Patients, especially young children, receiving vancomycin for a long clinical course should undergo careful monitoring of laboratory indicators and blood tests.
publisher Sociedade Brasileira de Medicina Tropical - SBMT
publishDate 2018
url http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822018000600873
work_keys_str_mv AT chenquanyao vancomycininducedseverethrombocytopeniainayounginfant
AT wanjun vancomycininducedseverethrombocytopeniainayounginfant
AT yangjianhui vancomycininducedseverethrombocytopeniainayounginfant
AT linmin vancomycininducedseverethrombocytopeniainayounginfant
AT chenyao vancomycininducedseverethrombocytopeniainayounginfant
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