Undiagnosed acute HIV infection identified through RNA testing of pooled serum samples obtained during a dengue outbreak in São Paulo, Brazil

Abstract INTRODUCTION: Improving HIV diagnostics and treatment is necessary to end the AIDS epidemic. Pooled plasma can be used to identify patients with acute HIV disease, even before serological tests. During dengue outbreaks, patients having symptoms common to other acute viral diseases might seek medical care. METHODS: We evaluated HIV RNA in pooled seronegative dengue samples. RESULTS: After excluding individuals with a known HIV diagnosis, an HIV-1 prevalence of 0.73% [95% confidence interval (CI) 0.23-1.76; 4/546 samples] was found. CONCLUSIONS: Promoting strategies to diagnose these individuals and provide them with medical treatment might be instrumental for controlling the HIV epidemic.

Bibliographic Details

Main Authors:	Matsuda,Elaine Monteiro, Colpas,Daniela Rodrigues, Campos,Norberto Camilo, Coelho,Luana Portes Ozorio, Carmo,Andreia Moreira dos Santos, Brígido,Luís Fernando de Macedo
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Medicina Tropical - SBMT 2017
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822017000100110
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