Prevalence and genotype distribution of human papillomavirus: implications for cancer screening and vaccination in Henan province, China

Abstract: INTRODUCTION: To provide information for cervical cancer screening and vaccination in Henan province, China, the distribution of human papillomavirus (HPV) was analyzed. METHODS: The HPV genotypes were detected using gene array and flow-through hybridization. RESULTS: Overall, 38.1% (1,536/4,033) of the women were human papillomavirus deoxyribonucleic acid (HPV DNA) positive. The prevalence of high-risk HPV types was 32.4%. HPV 16 was the most prevalent genotype (8.9%), followed by HPV 52 (5.8%) and HPV 58 (4.4%). CONCLUSIONS: The data support close surveillance of women for cervical cancer screening, and HPV prophylactic vaccines including HPV16, HPV 52, and HPV 58 might offer greater protection in this area.

Saved in:
Bibliographic Details
Main Authors: Zhao,Jun-Wei, Xu,Jing-Jing, Yan,Min, Sun,Xiao-Xu, Shi,Guang, Ming,Liang
Format: Digital revista
Language:English
Published: Sociedade Brasileira de Medicina Tropical - SBMT 2016
Online Access:http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822016000200237
Tags: Add Tag
No Tags, Be the first to tag this record!