Phenotypic and genotypic profile of pyrethroid resistance in populations of the mosquito Aedes aegypti from Goiânia, Central West Brazil

ABSTRACTINTRODUCTION:The mosquito Aedes aegypti has evolved resistance to pyrethroid insecticides. The present study evaluated Ae. aegypti from Goiânia for the resistant phenotype and for mutations associated with resistance.METHODS:Insecticide dose-response bioassays were conducted on mosquitoes descended from field-collected eggs, and polymerase chain reaction (PCR) was used to genotype 90 individuals at sites implicated in pyrethroid resistance.RESULTS:All mosquito populations displayed high levels of resistance to deltamethrin, as well as high frequencies of the 1016Ile kdr and 1534Cys kdrmutations.CONCLUSIONS:Aedes aegypti populations in the Goiânia area are highly resistant to deltamethrin, presumably due to high frequencies of kdr(knockdown-resistance) mutations.

Bibliographic Details

Main Authors:	Chapadense,Francesca Guaracyaba Garcia, Fernandes,Everton Kort Kamp, Lima,José Bento Pereira, Martins,Ademir Jesus, Silva,Luana Carrara, Rocha,Welington Tristão da, Santos,Adelair Helena dos, Cravo,Pedro
Format:	Digital revista
Language:	English
Published:	Sociedade Brasileira de Medicina Tropical - SBMT 2015
Online Access:	http://old.scielo.br/scielo.php?script=sci_arttext&pid=S0037-86822015000500607
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